Bulk Monk Fruit Extract Powder Supplier — Mogroside V 25%–55%, B2B Wholesale
Valeherb supplies monk fruit extract powder (Siraitia grosvenorii, Luo Han Guo, 罗汉果) bulk wholesale in three standardized grades — 25–30%, 40–45%, and 50–55% Mogroside V by HPLC — with full COA documentation per batch. Mogroside V (CAS 88901-36-4) is the primary triterpene glycoside responsible for monk fruit’s sweetness intensity and bioactive properties.[1] FDA GRAS status and non-glycemic sweetness make it one of the few natural high-intensity sweeteners suited to both food & beverage reformulation and nutraceutical clean-label positioning.
On this page: the mogroside compound profile, the three HPLC-standardized grades and sweetness reference data, grade-selection guidance, formulation applications, and regulatory status across key markets.
What Mogroside V Is and Why Grade Matters
Monk fruit contains a family of triterpene glycosides called mogrosides (Mogroside II through VI). Mogroside V — with five glucose units on a cucurbitane-type backbone — is the dominant compound for both sweetness and bioactivity. Its biosynthetic pathway was mapped by Itkin et al. (2016) in a PNAS study identifying the enzyme families responsible for the unique glucosylation sequence that produces its high-intensity sweetness.[1]
Purity grade directly determines sweetness intensity, inclusion rate, and cost per unit of sweetness. A 25% and a 50% grade do not perform identically — they have different sensory profiles, solubility characteristics, and cost-per-gram implications. Getting the grade right before procurement avoids reformulation cycles downstream.
| Grade | Mogroside V (HPLC) | Sweetness vs. Sucrose (approx.) | Typical Application |
|---|---|---|---|
| Standard Extract | 25–30% | ~150–180× | Functional beverages, RTD drinks, baked goods, clean-label food reformulation — where inclusion volume is not a constraint |
| Mid-Purity Extract | 40–45% | ~200–220× | Nutraceutical capsules, protein powders, dietary supplements, reduced-sugar snacks |
| High-Purity Extract | 50–55% | ~230–250× | Applications with strict label requirements, low-inclusion-rate formats, blended sweetener systems, cosmetic formulations |
Bioactive Profile: Beyond Sweetness
The research below describes published activity for mogroside compounds. It is provided as scientific context for formulators, not as claims for any Valeherb product.
Mogrosides demonstrate free radical scavenging activity in published in vitro research. Xu et al. (2013) evaluated the antioxidant effects of mogrosides in a cell model under palmitic acid-induced oxidative stress, reporting reduced intracellular ROS and modulation of genes involved in glucose metabolism — findings in the antioxidant research literature for this compound class.[2]
Liu et al. (2018) assessed antiglycation and antioxidant activity of mogroside extract in a protein glycation model, reporting inhibition of advanced glycation end-product (AGE) formation. AGE inhibition is of interest in functional food science contexts independent of any disease positioning.[4]
Liu et al. (2021) examined Mogroside V in an LPS-induced neuroinflammation model using BV-2 microglia cells, reporting inhibition of TNF-α, IL-1β, and IL-6 via TLR4-MyD88 pathway suppression and Nrf2 activation — preclinical inflammatory-pathway research in a central nervous system cell model.[3]
Formulation Applications
- Sugar-reduced food and beverage reformulation: Standard and mid-purity grades for clean-label RTD beverages, functional shots, protein powders, and baked goods. Monk fruit extract pairs well with erythritol — the combination improves mouthfeel and reduces erythritol’s cooling effect, producing a more sucrose-like sensory profile. Non-glycemic and zero-calorie status supports sugar-free, no-added-sugar, and keto-aligned label positioning
- Nutraceutical capsules and supplements: Mid-to-high-purity grades where Mogroside V content declaration supports premium positioning. Sweetness at low inclusion rates reduces the need for additional sweetener excipients in capsule and powder formats
- Blended natural sweetener systems: Monk fruit extract combined with stevia, allulose, or erythritol for cost-optimized systems with complementary flavor profiles. Monk fruit’s clean sweetness profile masks stevia’s bitterness at low inclusion rates
- Topical and ingestible cosmetics: High-purity extract (50–55%) for antioxidant-positioned formulations. Water-soluble grades available for aqueous cosmetic systems
Monk Fruit vs. Other Natural Sweeteners
| Sweetener | Primary Compound | Sweetness vs. Sucrose | Glycemic | Notable Formulation Consideration |
|---|---|---|---|---|
| Monk fruit extract (Mogroside V) | Triterpene glycosides | 150–250× | Non-glycemic | Clean sweetness profile, heat-stable, FDA GRAS, no known bitter aftertaste at recommended levels |
| Stevia (Rebaudioside A) | Diterpene glycosides | 200–350× | Non-glycemic | Detectable bitterness / licorice note at higher concentrations; often blended with monk fruit to improve profile |
| Erythritol | Sugar alcohol | ~60–70% | Non-glycemic | Cooling effect at high use levels; commonly blended with monk fruit to improve mouthfeel |
| Allulose | Rare sugar | ~70% | Non-glycemic (US FDA) | Maillard browning in baking; EU Novel Food approval process ongoing at last regulatory update |
Regulatory Status
- United States: FDA GRAS status for use as a sweetener across food and beverage categories. Non-glycemic — does not raise blood glucose. Structure/function claims on supplement products require marketer substantiation and FDA disclaimer. FDA-registered facility (21 CFR Part 111)
- European Union: Approved novel food sweetener under EU Regulation 2015/2283 — confirm category and use-level compliance with regulatory counsel for specific applications
- China (GB): Siraitia grosvenorii extract approved as food additive and functional ingredient — relevant for domestic and export documentation
- Canada, Japan, Australia: Regulatory approvals in place; category conditions vary by market — confirm with a local regulatory consultant for finished product applications
Sourcing Criteria for B2B Buyers
| Criterion | What to Require |
|---|---|
| Mogroside V Standardization | HPLC-verified Mogroside V % per batch — not total mogroside, which includes lower-potency glycosides that inflate readings without proportional sweetness contribution |
| Full Mogroside Profile | For premium applications: request the full mogroside profile breakdown to confirm absence of bitter-tasting lower glycosides (Mogroside II–III) |
| Water Solubility | For beverage applications: confirm water-solubility data and clarity at your target use level. Request 1% aqueous solution clarity test results |
| Heavy Metals & Pesticides | ICP-MS heavy metals (Pb, As, Cd, Hg) per batch — USP <232> limits. Multi-residue pesticide screen per batch |
| Complete COA | Mogroside V % (HPLC), heavy metals, pesticide residues, microbial limits (USP <2021>), moisture — per production batch from accredited laboratory |
| Certifications | Non-GMO; Kosher/Halal for relevant markets; FDA-registered facility (21 CFR Part 111) |
